A Prospective Single-center Cohort Study of Surgical Treatment of Chronic Rhinosinusitis

Launched by BEIJING TONGREN HOSPITAL · Aug 21, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the surgical treatment options for patients with Chronic Rhinosinusitis (CRS), a condition that causes long-lasting symptoms like nasal congestion, runny nose, facial pain, and a reduced sense of smell. The trial aims to gather more information about how effective surgery can be for different types of CRS, especially for those who haven’t found relief with medications. By collecting data from patients undergoing surgery, the researchers hope to provide better guidance for doctors in making treatment decisions.

To join the study, participants must meet certain criteria, including having a diagnosis of CRS as per specific guidelines and not finding relief from standard drug treatments. They also need to be willing to follow the study procedures. Participants can expect to receive care related to their surgery and contribute to important research that may help improve treatments for others with this condition in the future. This study is currently recruiting and welcomes patients of all ages and genders who fit the eligibility criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • (1) Meeting the CRS diagnostic criteria in the Chinese Guidelines for the Diagnosis and Treatment of Chronic Sinusitis (2018); (2) The effect of conservative drug treatment is not good or there are indications of surgery; (3) Good compliance, able to complete clinical observation. Compliance with guidelines
• Exclusion Criteria:
• • (1) The patient has conditions or co-existing diseases that may preclude the primary efficacy endpoint evaluation, such as benign or malignant tumors of the nasal cavity; (2) Clinically significant co-existing diseases that may interfere with clinical efficacy results, including but not limited to: Cystic fibrosis, eosinophilic granuloma with polyvasculitis (Churg-Strauss syndrome), granuloma with polyvasculitis (Wegener's granuloma), Young's synthesis, tuberculosis or other pathogen infection, malignancy, etc. (3) The patient had other medical or non-medical conditions that the investigator considered unsuitable for participation in the study.