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Search / Trial NCT06017011

Clinico-Radiological Characterisation for Remission of Acute Charcot-Neuroarthropathy of Foot.

Launched by POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH · Aug 23, 2023

Trial Information

Current as of August 20, 2025

Recruiting

Keywords

Charcot Neuroarthropathy F18 Fluoride Pet Scan Mri Of The Foot Rankl Osteoprotegerin

ClinConnect Summary

This clinical trial is exploring a condition called acute Charcot neuroarthropathy, which mainly affects people with diabetes. This condition causes inflammation and swelling in the foot, making it red and warm. It can often be confused with other issues, like infections or sprains. The standard treatment involves wearing a special cast that helps relieve pressure on the foot. The goal of this trial is to better understand how to monitor the healing process of this condition using advanced imaging techniques like MRI and a special type of PET scan. These methods will help doctors measure progress more accurately and determine the best time to stop treatment.

To be eligible for the trial, participants must have diabetes and be diagnosed with acute Charcot neuroarthropathy in one foot. The study is open to individuals of all ages and health backgrounds, except for those with certain conditions that prevent MRI scans or those who have recent infections or specific bone-related treatments. If you join the study, you'll undergo various imaging tests to assess your condition and help researchers find better ways to manage and treat this challenging disease.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients with Diabetes,
  • 1. Diagnosed both clinically as well as radiologically to be having unilateral acute charcot neuro-arthropathy.
  • 2. Irrespective of age, glycemic status, CKD staging.
  • Exclusion Criteria:
  • -1) The patients who are contraindicated for MRI like metallic implants, Pace maker in situ.
  • 2) Active infected foot ulcers 3) Osteomyelitis 4) Patients on drugs altering bone metabolism like bisphosphonates, teriparatide, Denosumab in the past 2 months.

About Post Graduate Institute Of Medical Education And Research, Chandigarh

The Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh is a premier institute dedicated to advancing medical education, research, and healthcare delivery in India. Renowned for its commitment to excellence, PGIMER plays a pivotal role in conducting cutting-edge clinical trials that contribute to the development of innovative therapies and improve patient outcomes. With a multidisciplinary approach and a team of highly qualified professionals, PGIMER fosters a collaborative environment for research, aiming to enhance medical knowledge and practice through rigorous scientific inquiry and evidence-based solutions.

Locations

Chandigarh, , India

Patients applied

0 patients applied

Trial Officials

Ashu Rastogi, MD, DM

Principal Investigator

PGIMER, Chandigarh

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported