Wired Magnetically Assisted Capsule Endoscopy and Esophageal Varices

Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Aug 24, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at two different methods for checking the esophagus (the tube that carries food from the mouth to the stomach) in patients with a liver condition called biliary atresia, particularly to see if they have a problem called esophageal varices. The two methods being compared are the traditional endoscopy, which involves using a tube that goes through the mouth, and a new technique called wired magnetically assisted capsule endoscopy (MACE), which allows doctors to examine the esophagus without needing to put anything in the mouth. One of the goals of the trial is to see if MACE is safer and more comfortable for patients and if it creates fewer droplets, which is important for preventing the spread of germs.

To participate in this trial, patients need to be over 6 years old and have stable vital signs, meaning their heart rate and breathing are normal, and they should not be experiencing any severe bleeding. However, some individuals won't be eligible if they have certain medical devices in their bodies, like pacemakers, or if they have trouble swallowing. Participants will either undergo the traditional endoscopy or the new capsule method and will be closely monitored throughout the process. This trial is currently recruiting participants, and it aims to gather valuable information that could improve how doctors diagnose this condition in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Biliary atresia patients \> 6 years old
• • Vital signs are stable
• • Without acute gastrointestinal bleeding
• Exclusion Criteria:
• • Patients with metal implants, metal stent, artificial joints, bone plates, and bone screw
• • Patients with electronic devices, such as pacemakers, cochlear implants, or other implanted electronic medical devices
• • Throat or esophageal obstruction leading to dysphagia patients
• • Consciousness disturbance patients unable to swallow
• • Patients with acute upper gastrointestinal bleeding
• • Patients with platelet lower than 40K or PT INR \> 1.5