Analysis of Stem and Non-Stem Tibial Component

Launched by JACOB M. ELKINS · Aug 30, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different types of knee implants affect outcomes for women with obesity who are having total knee replacement surgery. Specifically, it will look at whether using a stemmed tibial component (which is part of the knee implant that goes deeper into the bone) leads to lower rates of complications such as varus collapse (which is when the knee bends inward) and aseptic loosening (when the implant becomes loose without infection). The trial aims to help understand which type of implant might work better for women facing these challenges.

To participate in this study, you need to be a female adult with severe osteoarthritis who is planning to have a total knee replacement and has a body mass index (BMI) of 35 or higher. You can be either pre-menopausal or post-menopausal, but you should not have any recent infections or previous knee surgeries on the same knee. If you join the study, you will contribute to important research that could improve knee surgery outcomes for women like you. The trial is currently recruiting participants from the clinic where the study is being conducted.

Gender

FEMALE

Eligibility criteria

• Inclusion criteria:
• • Female adult patients with severe osteoarthritis scheduled to have primary total knee arthroplasty
• • 35 kg/m2 and above
• • Only patients from the PI's clinic will be included.
• • Women who are still menstruating and are currently on contraceptives and women who are in menopause.
• Exclusion Criteria:
• • Patients who have some active local or widespread infection (including secondary or inflammatory osteoarthritis)
• • medical conditions that put them at risk of complications or death during and after the study would not be eligible for surgery
• • Patients with previous knee surgery on arthroplasty site will be excluded
• • Pregnant patients and women who are capable of getting pregnant