Pattern of Autoimmune Hepatitis in Children In Sohag University Hospital

Launched by SOHAG UNIVERSITY · Aug 27, 2023

Keywords

ClinConnect Summary

This clinical trial is studying autoimmune hepatitis (AIH) in children at Sohag University Hospital. Autoimmune hepatitis is a condition where the body's immune system mistakenly attacks the liver, leading to inflammation. If not treated, it can worsen and cause serious liver damage. The study aims to understand how this disease presents in children and how it can be effectively diagnosed and treated.

To participate in the trial, children must be under 18 years old and show signs of autoimmune hepatitis. However, children with certain conditions, such as hepatitis B or C, or those who haven’t responded to previous treatments, cannot join. Participants will undergo tests to confirm the diagnosis, which may include blood tests and possibly a liver biopsy, where a small sample of liver tissue is taken for examination. The main treatment for AIH usually involves medications to suppress the immune system, helping to reduce liver inflammation. This study is important because it will help improve understanding and management of autoimmune hepatitis in young patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age: under 18 years old.
• • Both sex.
• • children suffering from manifestations of Autoimmune Hepatitis. Children previously Diagnosed with Autoimmune Hepatitis
• Exclusion Criteria:
• • Patient infected with hepatitis B or C.
• • Patient had autoimmune hepatitis after liver transplantation.
• • Patients not respond to steroids and immunosuppressive therapy. Other Causes of acute and chronich hepatitis like wilson disease and Metabolic liver Diseases