Comparing Innovative and Traditional Ventilation Strategies on Atelectasis and Prognosis in Elderly Patients

Launched by FUJIAN MEDICAL UNIVERSITY UNION HOSPITAL · Aug 28, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different methods of helping patients breathe during and after surgery can affect the health of elderly individuals. Specifically, it compares new, innovative breathing techniques to traditional ones to see if they can better prevent complications like atelectasis, which is when part of the lung collapses, and other breathing-related issues after surgery. The goal is to find out which method is safer and more effective for older patients undergoing laparoscopic abdominal surgery.

To be eligible for this trial, participants must be at least 60 years old and scheduled for laparoscopic surgery, a type of minimally invasive surgery. They should have a healthy body weight and not have serious lung or heart conditions. If chosen to participate, patients can expect to receive either the innovative or traditional breathing support during their surgery, and their recovery will be closely monitored to see how well they do afterward. This study is important because it aims to improve care for elderly patients, making their surgeries safer and helping them recover better.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Elderly patients aged ≥ 60 years old who undergo laparoscopic abdominal surgery；
• • 2. Body mass index（BMI） \<30；
• • 3. American society of anesthesiologists physical status classification system（ASA）:I-III；
• • 4. When the patient inhales air before surgery, SPO2≥94%；
• • 5. The duration of the operation is 2-7 hours, and the pneumoperitoneal pressure is 10-14mmHg.
• Exclusion Criteria:
• • 1. Patients with acute respiratory distress syndrome or pulmonary hypertension (pulmonary systolic blood pressure ≥ 40mmHg) or bronchiectasis or lung malignant tumors
• • 2. Patients with acute respiratory infections within one month before surgery
• • 3. Patients who have undergone cardiopulmonary surgery
• • 4. Receiving invasive mechanical ventilation for more than 30min within 30 days before surgery
• • 5. Patients with peak airway pressure \> 35 cm H2O during intraoperative mechanical ventilation
• • 6. Patients with severe organic lesions of the heart such as obvious heart failure and coronary heart disease
• • 7. Patients with preoperative anemia (Hb\<10g/L)
• • 8. Patients with hypoproteinemia before surgery (albumin \< 35 g/L)
• • 9. Patients with tracheostomy and severe difficult airway
• • 10. Patients with sleep apnea syndrome
• • 11. Patients with intraoperative heavy bleeding (50% of the circulating blood volume is lost ≥ 3 hours)
• • 12. Patients with mental illness, impaired consciousness and communication disorders
• • 13. Patients who refuse to participate in this trial