Hepatitis B Vaccination After Neonatal Surgery

Launched by CHILDREN'S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY · Sep 1, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating whether it's safe and effective to give the hepatitis B vaccine to newborns after they have had surgery on their digestive system. The goal is to better understand the best timing for vaccinations in these situations, as current practices vary widely and lack clear guidelines. The study will follow babies who need the vaccine after their surgeries, checking for any side effects and measuring their immune response to the vaccine.

To be eligible for this trial, participants must be full-term newborns who have undergone staged gastrointestinal surgery, and they must not have any serious health issues or infections. Participants can expect to receive their hepatitis B vaccinations and will be monitored for any reactions. This research aims to provide clearer recommendations for healthcare providers and families, ensuring that all newborns get the best possible care after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Term neonates; 2. Underwent staged gastrointestinal surgery; 3. HBsAg-; 4. No immune system disease; 5.no serious defect of heart, brain, liver, kidney and other organs.
• Exclusion Criteria:
• • 1. Premature; 2. HBsAg+; 3. Having immune system diseases; 4. Having serious defect of heart, brain, liver, kidney and other organs; 5. Lost patients.