Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

Launched by NORTHWELL HEALTH · Aug 28, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating the link between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG). OSA is a condition where a person has trouble breathing during sleep, leading to less oxygen in the body, while NTG is a form of glaucoma that can damage the optic nerve without high eye pressure, making it harder to detect. The researchers want to see if treating OSA with a device called CPAP (which helps keep the airway open during sleep) can improve blood flow to the retina and possibly help with early signs of vision problems.

To take part in this trial, you need to be at least 21 years old, newly diagnosed with OSA, and have good vision (20/40 or better). You should also be able to follow instructions and attend all study visits. However, if you have certain eye conditions or have had specific eye surgeries in the past, you may not be eligible. Participants will receive treatment for OSA and undergo tests to monitor their vision and eye health throughout the study. This research could provide valuable insights into preventing vision loss for those affected by these conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Newly diagnosed subjects with OSA that will undergo CPAP treatment.
• • At least 21 years of age
• • Best corrected vision of 20/40 or better, spherical Rx \< ± 6.0 Diopter, and cylinder \<-3.0D
• • Ability to follow instructions, and intent to complete all study visits
• Exclusion Criteria:
• • High Rx \>± 6.0D and cylinder \> -3.0D
• • Narrow angle glaucoma
• • History of any of the following: severe eye trauma, ocular inflammation, previous intraocular surgery except for uncomplicated cataract extraction with posterior chamber intraocular lens implantation.
• • Any medical or ocular condition which is not appropriate for participation in the trial (Diabetic retinopathy, and other retinal changes preventing reliable optic disc evaluation) Hypersensitivity to any component of altafluor benox