Safely Reduce Cystoscopic Evaluations for Hematuria Patients

Launched by ERASMUS MEDICAL CENTER · Aug 30, 2023

Keywords

ClinConnect Summary

The SeARCH-trial is a clinical study aimed at improving the way we diagnose patients who have microscopic hematuria, which means they have blood in their urine that can only be seen under a microscope. The researchers want to see if using a special urine test as the first step can be just as effective as traditional cystoscopic evaluations, which are more invasive tests that involve looking inside the bladder. This trial is open to men aged 40 and older and women aged 50 and older who have been confirmed to have microscopic hematuria.

If you qualify and choose to participate, you will provide urine samples for testing and may be monitored for any symptoms related to your condition. It's important to note that individuals with a history of bladder cancer, those with visible blood in their urine, or women who are pregnant or might become pregnant cannot participate in this study. The goal of the trial is to find a safer and more efficient way to evaluate patients, which could lead to better care for those with potential bladder issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Microscopically confirmed microscopic hematuria of voided urine defined as ≥3 erythrocytes per high power field
• • Male patients ≥40 years
• • Female patients ≥50 years
• Exclusion Criteria:
• • History of urothelial bladder- or urinary tract cancer
• • Presence of macroscopic (visible) hematuria
• • Woman who is or may be pregnant