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Search / Trial NCT06026592

Detection of Plasma DNA of Renal Origin in Kidney Transplant Patients

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Aug 30, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Epigenetic Renal Cell Free Dna Transplantation Biomarkers

ClinConnect Summary

This clinical trial is studying a new way to monitor kidney transplant health by looking at tiny pieces of DNA in the blood. Researchers believe that measuring specific markers in the blood can help them understand how well a transplanted kidney is working and whether it is being rejected by the body. This is important because detecting rejection early can lead to better management and outcomes for kidney transplant patients.

To be part of this study, you need to be at least 18 years old and have end-stage renal failure, meaning your kidneys are not working well enough and you are scheduled for a kidney transplant at Pitié Salpêtrière Hospital. If you join, you will provide blood samples before and after your transplant for testing. The study is currently looking for participants, and it is important to note that individuals under legal protective measures, such as guardianship, cannot take part. This study aims to improve our understanding of kidney transplants and help ensure better care for patients like you.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age ≥ 18 years old
  • With end-stage renal failure
  • Summoned for a kidney transplant at Pitié Salpêtrière Hospital
  • Having been informed of the study and not objecting to the study having given free and informed written consent for the genetic analysis
  • Benefiting from a social security scheme (excluding AME)
  • Exclusion Criteria:
  • Under legal protective measures (curatorship or guardianship, under judicial safeguard).

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Paris, , France

Paris, Ile De France, France

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported