The Retain Your Brain Health Study (RetainYourBrain.com)

Launched by RETAIN HEALTH, INC · Aug 30, 2023

Keywords

ClinConnect Summary

Alzheimer's disease (AD) is a public health crisis with few effective treatments. Most people are unaware that AD begins in the brain decades before the first symptoms of memory loss begin. That leaves a lot of time for people to learn their individual risk factors for AD and cognitive decline and take memory assessment screening tests in an effort toward the prevention or delay of dementia. To reach a growing at-risk population, mobile health technologies accessible via cell phone can fill an unmet need due to their accessibility and cost-effective delivery of care. Online education and te...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • be at least 53 years of age
• • have a family history of Alzheimer's Disease (AD)
• • have a compatible phone/device (phone allowing text messages and with internet access, and/or tablet device with the same capabilities)
• • a minimum of one of the following risk factors: body mass index (BMI) of \< 25 kg/m2, history of pre-diabetes/diabetes, high blood pressure, high cholesterol, smoking, low physical activity, low fish intake (\< 3 times per month), high alcohol intake (\< 7 servings per week for a women and \<14 servings a week for men), diagnosed with mild or moderate depression.
• Exclusion Criteria:
• • have a diagnosis of dementia due to AD
• • other dementia
• • women who are currently pregnant or who plan on becoming pregnant in the next 6 months
• • BMI \<18.5 kg/m2
• • consuming \>35 alcoholic drinks/week for men or \>28 alcoholic drinks/week for women
• • severe depression (PHQ-9 score of more than 15)
• • current treatment for cancer
• • diagnosis of Parkinson's disease, amyotrophic lateral sclerosis, Lewy body dementia, frontotemporal disorders, multiple sclerosis, or other neurodegenerative disease
• • current treatment for an eating disorder
• • currently prescribed insulin for type I or II diabetes
• • inability to give informed consent or complete identity verification
• • participating in another AD trial.