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Search / Trial NCT06027515

Esophageal Cancer Multimodal Prehabilitation Study

Launched by MASSACHUSETTS GENERAL HOSPITAL · Sep 6, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Esophageal Cancer Esophageal Neoplasms

ClinConnect Summary

The Esophageal Cancer Multimodal Prehabilitation Study is a research trial aimed at helping older patients with esophageal cancer get ready for surgery. The study will explore a prehabilitation program designed to improve physical fitness, nutrition, and sleep quality before surgery. This approach is especially important for older adults who may be at higher risk during surgical procedures.

To participate in this study, you need to be 65 years or older, have completed chemotherapy or radiation for esophageal cancer, and have at least four weeks before your scheduled surgery. The study is open to all genders, but participants should be able to speak English and agree to join the study. During the trial, you can expect to engage in activities that enhance your overall health, which may help improve your surgical outcomes. It's important to note that if you have certain dietary restrictions, skin conditions, or severe physical disabilities, you may not be eligible for this study. If you're interested in participating, this could be a valuable opportunity to support your health before surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 65 years of age and over
  • Adult male or non-pregnant female volunteers
  • Completed neoadjuvant chemotherapy or radiotherapy for esophageal cancer
  • At least four weeks to esophageal cancer surgery
  • Without skin conditions that preclude wearing sensors
  • Able to speak English and consent
  • Exclusion Criteria:
  • Participants in any other interventional study that may bias results or limit study adherence during our study
  • Dietary restrictions that prevent consumption of nutritional supplements
  • Women who are pregnant, nursing, or at risk of becoming pregnant
  • Profound physical disability (for example, quadriplegia) that precludes participation in any aerobic or strength training.

About Massachusetts General Hospital

Massachusetts General Hospital (MGH) is a leading academic medical center located in Boston, Massachusetts, renowned for its commitment to advancing medical research and patient care. As a prominent teaching hospital affiliated with Harvard Medical School, MGH plays a pivotal role in clinical trials across a wide range of disciplines, including cardiology, oncology, neurology, and more. The institution is dedicated to fostering innovative research that translates into effective therapies and improved health outcomes. MGH's Clinical Trials Office provides comprehensive support to facilitate the design, implementation, and management of clinical studies, ensuring adherence to the highest ethical standards and regulatory compliance. With a focus on collaboration and patient-centered care, MGH strives to enhance medical knowledge and contribute to the future of healthcare.

Locations

Boston, Massachusetts, United States

Patients applied

0 patients applied

Trial Officials

Hassan Dashti, PhD

Principal Investigator

Massachusetts General Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported