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Search / Trial NCT06027528

Evaluation of Socket Preservation Using Autogenous Dentine Graft With Or Without Autologous Fibrin Glue

Launched by CAIRO UNIVERSITY · Aug 31, 2023

Trial Information

Current as of August 26, 2025

Not yet recruiting

Keywords

Socket Preservation Alveolar Ridge Preservation Dentin Graft Autologous Fibrin Glue Sticky Dentin Sticky Graft

ClinConnect Summary

This clinical trial is studying a dental procedure called socket preservation, which helps to maintain the shape of the jawbone after a tooth is removed. The researchers want to find out if using a special mixture of dentin graft (a type of natural tooth material) and a substance called autologous fibrin glue (which helps promote healing) is better for preserving bone shape than using dentin graft alone. They will measure changes in the width and height of the jawbone both before and after the procedure.

To participate in this study, you need to be a healthy adult, at least 18 years old, and a non-smoker. You should have a tooth that can’t be saved, such as one with a fracture or severe decay, and the area where the tooth was removed should be healthy. However, if you have certain health conditions or a history of specific treatments like chemotherapy or radiation, you may not be eligible. Participants can expect to attend follow-up visits to monitor their healing and the changes in their jawbone. This study aims to improve dental procedures and outcomes for patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Systemically healthy patients ≥18 years old
  • Nonsmoker
  • Teeth with root fracture, teeth with failed endodontic therapy or advanced caries
  • Intact extraction socket with no dehiscence or fenestration.
  • Exclusion Criteria:
  • Patients with systemic diseases.
  • Patients with dehiscence or fenestrations
  • Patients with presence or history of osteonecrosis of the jaws, with use of bisphosphonates, exposure to head and neck radiation, chemotherapy.
  • Patients with large distinct pre-apical pathology
  • Smokers of more than 10 cigarettes a day or equivalent to cigarettes
  • Breastfeeding or pregnant women
  • Patients without availability to attend follow-up visits or patients rejecting to sign the informed consent.

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Patients applied

0 patients applied

Trial Officials

Amr Zahran, Professor

Study Director

Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported