B-mode Ultrasound, Sono-Elastography, and Diffusion-weighted Imaging MRI in Thyroid Nodules

Launched by ASSIUT UNIVERSITY · Sep 1, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at different imaging techniques to better understand thyroid nodules, which are lumps in the thyroid gland. Researchers want to compare how well traditional ultrasound methods, a special type of ultrasound called elastography, and a type of MRI known as diffusion-weighted imaging work in identifying and distinguishing these nodules. The goal is to find out which method is the most accurate for determining whether these nodules are benign (non-cancerous) or malignant (cancerous).

To participate in this trial, patients need to have a normal bleeding profile and present with either one or multiple thyroid nodules. If there are multiple nodules, researchers will focus on the one that looks suspicious based on ultrasound features. Some people may not be eligible, such as those with certain bleeding disorders, mainly cystic nodules, or specific conditions that make MRI unsafe. Participants will undergo imaging tests but will not be recruited until the trial officially begins. This study aims to improve how doctors evaluate thyroid nodules, which can lead to better patient care and outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients should have a normal bleeding profile.
• • Presence of solitary or multiple nodules in the thyroid gland.
• • In the case of patients having multiple nodules, the nodule having suspicious ultrasound features (having TI-RADS score 4 or 5) was selected for further analysis.
• • The nodules were either solid or mixed (containing both solid and cystic parts) with a predominant solid component
• Exclusion Criteria:
• • Contraindicated biopsy (as thrombocytopenia or bleeding disorder).
• • Patient with cystic and mainly cystic nodules (TI-RADS 1 nodules).
• • Nodules with complete shell-calcification which may cause color mapping artifacts.
• • MRI contraindications such as Claustrophobia, MR-incompatible pacemakers, and MR-incompatible prosthetic heart valves.
• • Patients with recurrent thyroid masses.
• • History of operative procedure, chemo, or radiotherapy on the thyroid gland.
• • Declined consent.