Efficacy of Hydrogen Peroxide ( H2O2) in Controlling Placental Site Bleeding in Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)

Launched by CAIRO UNIVERSITY · Sep 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of hydrogen peroxide (H2O2) to help control bleeding during cesarean deliveries in women with a condition called placenta accreta spectrum (PAS). PAS occurs when the placenta grows too deeply into the uterine wall, which can lead to severe bleeding during birth. The trial aims to see if hydrogen peroxide can help reduce this bleeding and make the surgery safer for mothers with this condition.

To participate in this trial, women must be between 18 and 40 years old, have a body mass index (BMI) under 35, and be diagnosed with placenta previa along with a mild form of placenta accreta (FIGO grade 1). Participants will need to be stable and not experiencing major bleeding during surgery. If eligible, women can expect to receive hydrogen peroxide during their surgery to help manage bleeding. This trial is currently recruiting participants, and it’s important to know that only women who meet the specific health criteria will be considered for the study.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age from 18-40 years
• • BMI \< 35 kg/m2
• • Pregnant patients with placenta previa .
• • Placenta accrete FIGO grade 1 .
• • Vitally stable .
• • Candidate for conservative management.
• • No major intra-operative bleeding.
• Exclusion Criteria:
• • Vitally unstable .
• • Massive pre- or intra-operative bleeding.
• • Medical disorders ( e.g. : hypertension , cardiac .... )
• • Placenta accrete , FIGO grades 2 or 3 .
• • Not indicated for conservative management.