PrEPared-RN, CAN Nurse-Led Management of High-risk Patients for Pre-Exposure Prophylaxis (PrEP)

Launched by CAN COMMUNITY HEALTH · Sep 7, 2023

Keywords

ClinConnect Summary

The PrEPared-RN clinical trial is studying a new way to help high-risk individuals prevent HIV infection using a treatment called PrEP (pre-exposure prophylaxis). In this trial, specially trained nurses will guide participants through the process of getting tested for HIV and sexually transmitted infections (STIs), as well as provide counseling about the importance of these tests. If a participant tests negative for HIV, they will receive medications (either Truvada or Descovy) to help protect them from HIV. Throughout the study, nurses will also check in on participants' general health and any challenges they face, like access to transportation or housing, which can affect their ability to stay on PrEP.

To be eligible for this trial, participants should be between 18 and 65 years old and at risk for HIV. This includes gay and bisexual men of color, transgender individuals, and heterosexual men and women, among others. However, people who are currently HIV positive, younger than 18, or have certain health conditions may not qualify. Overall, participants can expect a supportive environment where nurses will closely monitor their health and help them stay on track with their HIV prevention plan.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Gay and bisexual men of color, cisgender women of color, and transgender women, transgender men, heterosexual men, Caucasian cisgender men and women individuals at risk for HIV and STI's, Individuals completing nPEP services. Between the ages of 18 and 65.
• Exclusion Criteria:
• • Minors younger than age 18, individuals not at risk for HIV, HIV positive status, HIV seroconversion, current or historical Hepatitis B virus infection, patients who are candidates for Truvada; patient has a history of renal dysfunction or eGFR values are below 60 mL/min, patients who are candidates for Descovy; patient has advanced CKD or an eGFR less than 30 mL/min, Patient is taking contraindicated medications\*, patient has a positive pregnancy test or is breastfeeding. Any other clinical or psychosocial condition or prior therapy that, in the opinion of the Investigator, would make the participant unsuitable for the study or unable to comply with dosing requirements