Measuring Environmental Tobacco and Cannabis: Pollutants and Exposures

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Sep 1, 2023

Keywords

ClinConnect Summary

This clinical trial is looking to understand how healthy nonsmokers are affected by exposure to secondhand cannabis smoke. It aims to gather information about the pollutants and substances that people might breathe in from their environment when they are around others who use cannabis. The study is open to adults between the ages of 21 and 50 who do not smoke cannabis or tobacco, have a healthy medical history, and can exercise moderately. Participants should also have normal blood pressure and body mass index (BMI).

If you are interested in joining this study, you will need to meet specific criteria. For example, you should be a healthy adult nonsmoker, not currently using cannabis or tobacco, and not have certain medical conditions like asthma or heart disease. Participants will be asked to answer questions about their health and lifestyle and will undergo some tests to ensure they qualify. This study has not started recruiting yet, so keep an eye out for updates if you think you might be eligible!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • -
• Adult nonsmokers, aged 21-50, who:
• • Are healthy on the basis of medical history
• • Have systolic blood pressure \<150
• • Have diastolic blood pressure \<100
• • Have BMI between 18.1 and 34.9
• • Able to perform moderate exercise,
• • Are not exposed to tobacco or cannabis SHS in their daily lives. (Nonsmoking status and low SHS exposure are determined by self-report on the screening questionnaire, salivary cotinine \< 10 ng/ml and THC \< 50 ng/m and exhaled CO2 below 4 ppm)
• Exclusion Criteria:
• • Current use of cannabis products, including CBD and edible THC products
• • Regular exposure to secondhand tobacco or cannabis smoke
• • Positive SARS-CoV-2 antibody test
• • Age 18 \< or \> 50
• • Physician diagnosis of asthma, heart disease, hypertension, thyroid disease, diabetes, renal or liver impairment or glaucoma.
• • Unstable psychiatric condition (such as current major depression, history of schizophrenia or bipolar disorder) or current use of more than two psychiatric medications
• • Systolic blood pressure \> 150
• • Diastolic blood pressure \> 100
• • Pregnancy or breastfeeding (by urine hCG and/or history)
• • Alcohol or illicit drug dependence within the past 5 years
• • BMI \> 35 and \< 18
• • Current illicit drug use (by history or urine test)
• • More than 1 pack year smoking history
• • Ever a daily marijuana smoker
• • Smoked anything within the last 2 months
• • Occupational exposure to smoke, dusts OR fumes
• • Concurrent participation in another clinical trial
• • Unable to communicate in English
• • No social security number