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Search / Trial NCT06033417

Walking and Blood Pressure in Older Adults With Respiratory Impairment.

Launched by IOWA STATE UNIVERSITY · Sep 5, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Physical Activity Step Counts Lung Function Blood Pressure Older Adults Walking

ClinConnect Summary

Older adults are particularly susceptible to respiratory impairment (a condition of lung dysfunction) due in part to longer lifetime exposures to air pollutants, tobacco smoke, and physical inactivity. Older adults with respiratory impairment have greater long-term risks of death by cardiovascular disease (CVD) when compared to individuals without respiratory impairment. Impaired lung function tends to run parallel with high blood pressure, and high blood pressure is a determinant of CVD mortality in this population. One approach to lowering blood pressure across the lifespan is by increasi...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Men and women aged 65 years and above.
  • Elevated systolic blood pressure (120mmHg - 159 mmHg), and/or individuals taking medications for high blood pressure with a systolic pressure less than or equal to 159mmHg.
  • Respiratory impairment as assessed by abnormal spirometry (a lung function test). Abnormal spirometric phenotypes include obstructive pattern, restrictive pattern, mixed obstructive/restrictive, and preserved ratio impaired spirometry (PRISm).
  • Non-smoker (defined as being tobacco-free for at least the previous 12-months).
  • Body mass index (BMI) \<42kg/m2.
  • Physically inactive (determined by a 7-day day assessment of step counts using a pedometer, and defined as having an average daily step count \<7,000).
  • Willingness to increase daily steps.
  • Exclusion Criteria:
  • History of stroke, heart attack, or cancer diagnosis in the last 6-months.
  • Admission to hospital for a respiratory-related illness (e.g., COPD exacerbation, pneumonia, lung injury, etc.) within the last 3 months.
  • The use of supplemental oxygen.
  • Neurological conditions such as Alzheimer's or Parkinson's disease.
  • Significant mobility limitation (e.g., severe arthritis) that would hinder the ability to increase daily steps.
  • The use of a cane or walker.
  • Participants engaged in another walking study or structured walking program.

About Iowa State University

Iowa State University (ISU) is a renowned research institution committed to advancing knowledge and improving health outcomes through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, ISU leverages its expertise in agriculture, engineering, and health sciences to conduct cutting-edge research that addresses pressing health challenges. The university's clinical trial programs are designed to uphold the highest ethical standards and regulatory compliance, fostering a safe environment for participants while contributing valuable insights to the medical community. ISU's dedication to education, research excellence, and community engagement positions it as a leader in the field of clinical research.

Locations

Ames, Iowa, United States

Patients applied

0 patients applied

Trial Officials

Duck-chul Lee, PhD

Principal Investigator

Iowa State University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported