Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach
Launched by THE FIRST AFFILIATED HOSPITAL WITH NANJING MEDICAL UNIVERSITY · Sep 11, 2023
Trial Information
Current as of November 11, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a technique called a brachial plexus block (BPB) to see how it affects patients undergoing a specific type of brain surgery called embolization for intracranial aneurysms. The surgery will be done using a method that accesses the arteries through the wrist (transradial approach). The researchers want to find out if using BPB can help reduce problems with the radial artery, which is the artery in the wrist, during and after the procedure. They will compare outcomes between patients who receive the BPB and those who do not.
To participate in this trial, you need to be between 18 and 75 years old and have a body mass index (BMI) under 28. You should be scheduled for elective surgery for an intracranial aneurysm and be able to give your consent to join the study. Participants will be monitored for any complications during the procedure and will have follow-up assessments to check the health of their upper limb arteries one month after surgery. It’s important to know that some people may not be eligible, such as those with allergies to local anesthetics or certain vascular conditions. If you decide to take part, the study will help doctors understand how to improve care during this type of surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 18-75 years old, BMI\<28kg/m2
- • ASA physical status Ⅰ-Ⅲ
- • Elective interventional surgery for intracranial aneurysms via TRA
- • willing to sign informed consent
- Exclusion Criteria:
- • patients allergic to local anesthetics
- • neck infection on the surgical side
- • Preoperative upper extremity ultrasound or DSA showed radial artery occlusion and arteriovenous fistula
- • The diameter of radial artery was still less than 2mm after brachial plexus block
- • Axillary artery occlusion and other vascular anatomical abnormalities may affect the operation
- • Radial artery patency: Barbeau type D
- • The history of hand trauma may affect the establishment of radial artery; access, or the use of radial artery as a bypass or dialysis vessel
- • patients with incomplete block effect after nerve block were detected;
- • The patient refused to participate in the study or cooperate with the follow-up
About The First Affiliated Hospital With Nanjing Medical University
The First Affiliated Hospital of Nanjing Medical University is a leading medical institution dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital is committed to implementing rigorous scientific methodologies to evaluate new therapies and treatment approaches. With a multidisciplinary team of experienced healthcare professionals and researchers, the hospital fosters a collaborative environment aimed at enhancing patient outcomes and contributing to the global medical community. Its strategic focus on translational medicine ensures that groundbreaking discoveries are efficiently translated into practical applications for patient care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Nanjing, Jiangsu, China
Patients applied
Trial Officials
Jingjin Li, M.D
Principal Investigator
The First Affiliated Hospital with Nanjing Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported