Evaluation of Cerebral Blood Flow and Cerebral Oxygenation With Transcranial Doppler and NIRS in Laparoscopic Cholecystectomy Cases

Launched by ULUDAG UNIVERSITY · Sep 6, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how certain changes in blood flow and oxygen levels in the brain occur during a specific type of surgery called laparoscopic cholecystectomy, which is commonly performed to remove the gallbladder. The researchers want to understand how a technique called pneumoperitoneum, which involves inflating the abdomen with gas to allow better access to the organs, affects blood flow in the brain. They will use two different methods, Near-Infrared Spectroscopy (NIRS) and Transcranial Doppler (TCD) ultrasonography, to measure these changes and see if one method is more effective than the other.

To participate in this trial, you need to be between 18 and 65 years old and scheduled for this type of surgery. The study is looking for patients in good health (classified as ASA 1-3), meaning they have no serious health issues. However, individuals with certain medical conditions, such as severe heart or vascular diseases, or those who have had a stroke, cannot participate. If you join the study, you can expect to have your brain's blood flow and oxygen levels monitored during your surgery to help researchers gather important information that may improve patient care in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with American Society of Anesthesiology (ASA) 1-3 classification,
• • Both male and female patients between the ages of 18 to 65,
• • Patients scheduled for elective laparoscopic cholecystectomy.
• Exclusion Criteria:
• • American Society of Anesthesiology (ASA) 4 and above patient groups,
• • Patients aged under 18 and over 65,
• • Patients with a history of known previous cerebrovascular accident (CVA),
• • Patients with follow-up due to Cerebrovascular Ischemic Brain Attack Syndrome (CIBAS),
• • Patients diagnosed with Carotid Stenosis,
• • Patients diagnosed with peripheral and central vascular diseases,
• • Patients with general debilitation and extreme senility,
• • Cases that require conversion to laparotomy during the intraoperative period.