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Search / Trial NCT06037161

Comparison of Two Methods of Covering a Single Lower Front Tooth With Receded Gums

Launched by CASE WESTERN RESERVE UNIVERSITY · Sep 7, 2023

Trial Information

Current as of September 03, 2025

Recruiting

Keywords

Connective Tissue Graft(s) Cosmetic Periodontal Plastic Surgery Gingival Recession Mucogingival Surgery Treatment Planning

ClinConnect Summary

This clinical trial is exploring two different methods for treating gum recession on a single lower front tooth. Gum recession can expose the roots of teeth, leading to sensitivity or other dental issues. The trial compares a traditional technique called Coronally Advanced Flap (CAF) with a newer method known as Gingival Pedicle Split Thickness flap (GPST), both of which involve the use of a connective tissue graft to help restore the gums. The goal is to see which method results in better coverage of the exposed tooth root and improves gum tissue health.

To participate in this study, individuals must be over 18 years old and have specific types of gum recession around their lower front teeth. Eligible participants should be generally healthy and not have any conditions that could complicate gum surgery, such as uncontrolled diabetes or smoking more than 10 cigarettes a day. If you join the trial, you will receive one of the two treatment methods and will be monitored to see how well the procedure works in terms of gum recovery and tissue regrowth. This is a great opportunity to contribute to dental research while potentially improving your own dental health.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Males and females of \> 18 years of age
  • Single Cairo's RT1 (Recession Type 1) and RT2 ( Recession Type 2) recession defects (≥3 mm in depth) in mandibular anterior teeth (Incisors).
  • Presence of identifiable cemento-enamel junction (CEJ)
  • Presence of a step ≤1 mm at the CEJ level and/or the presence of a root abrasion, but with an identifiable CEJ, will be accepted
  • Periodontally and systemically healthy patients
  • No contraindications for periodontal surgery and not taking medications known to interfere with periodontal tissue health or healing; and no prior periodontal surgery on the involved sites
  • Exclusion Criteria:
  • Vaping, chewing tobacco or smoking \> 10 cigarettes per day
  • Uncontrolled Diabetes Mellitus (HbA1c \> 7)
  • Pregnancy and Lactation
  • Diseases affecting connective tissue metabolism
  • Long-term steroid use
  • Recession defects associated with caries
  • Teeth associated with pulpal pathology

About Case Western Reserve University

Case Western Reserve University (CWRU) is a leading research institution located in Cleveland, Ohio, renowned for its commitment to advancing knowledge and improving health outcomes through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, CWRU integrates expertise from various fields, including medicine, engineering, and social sciences, to address complex health challenges. The university's clinical trial initiatives are designed to foster the development of novel therapies and interventions, ensuring rigorous scientific methodologies and ethical standards are upheld. CWRU is dedicated to translating research findings into tangible benefits for patients and communities, contributing significantly to the advancement of healthcare practices and policies.

Locations

Cleveland, Ohio, United States

Patients applied

0 patients applied

Trial Officials

Gian Pietro Schincaglia, DDS, PhD

Principal Investigator

Case Western Reserve University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported