Comparison of Quality of Life in Patients with Differentiated Thyroid Carcinoma Undergoing Different Surgery

Launched by SUN YAT-SEN MEMORIAL HOSPITAL OF SUN YAT-SEN UNIVERSITY · Sep 13, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how different types of surgery for thyroid cancer affect patients' quality of life. Thyroid cancer, especially the early form known as differentiated thyroid carcinoma, is becoming more common, particularly in women. The traditional method of surgery leaves a visible scar on the neck, while newer, minimally invasive techniques aim to reduce or eliminate this scar, potentially leading to better overall satisfaction and quality of life for patients. Researchers will be following patients regularly to assess their quality of life, voice, and the appearance of any scars using specific questionnaires.

To participate in this study, you need to be between 18 and 70 years old and have a confirmed diagnosis of early-stage differentiated thyroid cancer. You should be able to read and write in Chinese and be willing to attend follow-up appointments. If you have other types of thyroid cancer or a history of certain medical issues, you may not be eligible. Participants in the trial can expect regular check-ins and assessments to help determine if the newer surgery methods truly provide a better experience than the traditional approach.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years and \< 70 years;
• • Biopsy or surgical pathology indicated differentiated thyroid carcinoma (papillary thyroid carcinoma, follicular carcinoma);
• • stage T1\~T3a, N0\~N1a, M0;
• • Ability to read and write Chinese;
• • Willingness to follow up.
• Exclusion Criteria:
• • Age \< 18 years old or ≥70 years old;
• • Biopsy or surgical pathology indicated medullary carcinoma or anaplastic thyroid carcinoma;
• • Aggressive histology: tall cell, columnar cell, hobnail variant, etc.
• • Mixed with medullary carcinoma or anaplastic thyroid carcinoma;
• • High risk of recurrence (according to ATA guideline);
• • Lateral cervical lymph node metastasis or distant metastasis;
• • Suffer from other malignant tumors;
• • History of thyroid surgery or cervical lymph node dissection;
• • Cognition or behavior impairment.