Plasma Sodium and Sodium Administration in the ICU

Launched by UNIVERSITY HOSPITAL, LINKOEPING · Sep 7, 2023

Keywords

ClinConnect Summary

This clinical trial, titled "Plasma Sodium and Sodium Administration in the ICU," is focused on understanding how sodium levels are managed in patients who are critically ill. In particular, it looks at patients in the Intensive Care Unit (ICU) who often receive large amounts of sodium through various treatments. Researchers want to find out if this high sodium administration is really necessary and if doctors consider the total amount of sodium given when prescribing treatments. The trial aims to gather data on how different physicians might prescribe sodium differently.

To participate in this trial, patients need to be adults who have stayed in the ICU at the University Hospital of Linköping for at least seven days and have been discharged. They should also have a Body Mass Index (BMI) between 18.0 and 48.0 when they were admitted. However, patients who had very low or very high sodium levels upon arrival, or those with certain severe conditions, won't be eligible. Participants can expect to contribute to important research that may change how sodium is used in critical care, helping improve treatment for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult
• • Documented length of stay at the Central Intensive Care Unit (CIVA) at the University Hospital of Linköping of seven (7) days minimum.
• • The patient has been discharged from the ICU.
• • Body Mass Index (BMI) between 18.0 and 48.0 kg/m2 at admission.
• Exclusion Criteria:
• • The patient has previously been included in the study in connection with another ICU-admission.
• • The patient has a severe hyponatremia (\<129 mmol/L) upon arrival to the ICU.
• • The patient has a severe hypernatremia (\>149 mmol/L) upon arrival to the ICU.
• • The patient is severely hyperosmolar (\>330 mmol/L) upon arrival to the ICU.
• • The patient is severely hyperglycemic (\>30 mmol/L) upon arrival to the ICU.
• • The patient has an elevated serum urea (\>30 mmol/L) upon arrival to the ICU.
• • The patient receives any dialysis treatment during the observation time.
• • The patient is suspected to have an elevated intracranial pressure during the observation time or is suspected to have other intracranial pathology that is likely to affect sodium homeostasis
• • The patient has an intoxication with toxic alcohols as a primary diagnosis.