Biobanking for Biomarkers In Respiratory Disease, Allergic Diseases and/or Mast Cell Disorders

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Sep 7, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on collecting samples from patients who have allergic diseases, asthma, or mast cell disorders. The goal is to create a biobank, which is a collection of biological samples that researchers can use in the future to find new ways to diagnose and predict these conditions. By studying these samples, scientists hope to identify important markers that could help doctors understand more about these diseases and how to treat them better.

To participate in this trial, you need to be between the ages of 18 and 75 and have been diagnosed with one of the conditions mentioned, such as having a positive allergy test or asthma. If you join, you will provide samples that will be used for research, and you can expect to receive detailed information about the study and your role in it. It's important to note that pregnant or breastfeeding women and those under legal protection cannot participate. If you're interested and meet the criteria, this could be a great opportunity to contribute to important research that may help many people in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients with a positive prick test or specific IgE regardless of the allergen
• • patients suspected of allergic pathology defined by the need to carry out a prick test or specific IgE or a food or drug reintroduction test as part of the treatment
• • patients with systemic or cutaneous mastocytosis according to the international classification8
• • patients with mast cell activation syndrome according to the international classification8
• • patients with familial hyper-alpha tryptasemia on the presence of variation in the number of copies of the alpha allele of the TPSAB1 gene
• • patients with asthma of any severity
• • people affiliated or beneficiaries of a social security scheme
• • patients able to receive and understand the information on the study and their participation and having freely consented to it in writing before any collection of samples or data necessary for the research (no restriction of rights by the judicial authorities and mastery of the French language).
• Exclusion Criteria:
• • patients under legal protection, guardianship or curatorship
• • pregnant or breastfeeding women