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Search / Trial NCT06039969

Evaluate Aerobic Exercise on Myocardial Fibrosis and Intestinal Flora in Dilated Cardiomyopathy Diagnosed First Time.

Launched by NANJING MEDICAL UNIVERSITY · Sep 11, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Aerobic Exercise Rehabilitation Myocardial Fibrosis Human Gut Microbiome Cardiac Magnetic Resonance

ClinConnect Summary

This clinical trial is studying the effects of aerobic exercise on patients who have been diagnosed for the first time with dilated cardiomyopathy, a condition that affects the heart's ability to pump blood. The researchers want to see how exercise can change the balance of bacteria in the gut and improve heart health by reducing a condition called myocardial fibrosis, which means the heart muscle becomes stiff and less effective.

To participate in this study, you need to be between the ages of 65 and 74 and have been hospitalized for heart failure for the first time, with a confirmed diagnosis of dilated cardiomyopathy. Unfortunately, if you have other heart conditions, have previously been diagnosed with dilated cardiomyopathy, have a severe infection, or cannot perform certain heart tests, you won’t be eligible. If you join this trial, you can expect to engage in a structured exercise program designed to help your heart and overall health, while also contributing to important research that could benefit others in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1、Patients hospitalized for the first time because of heart failure 2、The patient who was definitely diagnosed as dilated cardiomyopathy for the first time
  • Exclusion Criteria:
  • 1、Other types of cardiomyopathy 2、Has been diagnosed as dilated cardiomyopathy. 3、malignant tumor 4、acute infection 5、Cannot perform cardiopulmonary exercise test.

About Nanjing Medical University

Nanjing Medical University is a leading institution in medical education and research, dedicated to advancing health care through innovative clinical trials and scientific inquiry. With a strong emphasis on translating research findings into practical applications, the university fosters collaboration among multidisciplinary teams to address pressing health issues. Committed to ethical standards and patient safety, Nanjing Medical University is at the forefront of clinical research, contributing valuable insights and advancements in medical science to improve patient outcomes and enhance public health.

Locations

Huai'an, Jiangsu, China

Patients applied

0 patients applied

Trial Officials

XiWen Zhang, MD

Study Director

Huai'an First People's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported