Effect of Treatments on Pain and Quality of Life in Individual With Burning Mouth Syndrome

Launched by FEDERAL UNIVERSITY OF MINAS GERAIS · Sep 10, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different treatments can help people with Burning Mouth Syndrome (BMS), a condition that causes a painful burning sensation in the mouth. The trial aims to understand how various therapies affect the pain levels and overall quality of life for adults suffering from this condition. It is particularly looking at treatments like systemic antidepressants, a topical medication called clonazepam, herbal remedies such as capsaicin, and a dietary supplement known as alpha-lipoic acid (ALA).

To participate in the trial, individuals must be between the ages of 65 and 75 and have experienced recurring oral pain that lasts for more than 2 hours a day for at least 3 months. Their oral health must appear normal, and they should not have any other serious health conditions or oral lesions. Participants can expect to receive different treatments and will be monitored for changes in their pain and quality of life throughout the study. This research is important because it aims to find effective ways to improve the lives of those affected by BMS, a condition that currently lacks a clear understanding and effective treatment options.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • burning mouth syndrome;
• • oral pain that recurs daily for \> 2 hours per day for \> 3 months;
• • pain with burning quality and felt superficially in the oral mucosa;
• • oral mucosa appears normal
• • oral clinical examination, including sensory tests, is normal;
• Exclusion Criteria:
• • pregnancy;
• • oral mucosal lesions;
• • systemic diseases such as diabetes, anemia, deficiency of vitamin B1, B2, B6, B12, Fe, Zinc, and folic acid;
• • gastroesophageal reflux;
• • previous head and neck radiotherapy;
• • Sjogren's disease;
• • allergies;
• • candidiasis;
• • unstimulated saliva flow \< 0.25 ml/min and stimulated flow \< 1.0 ml/min will be excluded;