AM vs PM Exercise Training

Launched by MICHIGAN STATE UNIVERSITY · Sep 6, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how the timing of exercise affects blood pressure in older women who have high blood pressure, also known as hypertension. Researchers want to find out if exercising in the morning or the evening can help improve blood vessel health and lower blood pressure in postmenopausal females. This is important because managing high blood pressure can reduce the risk of heart problems.

To participate in the trial, women need to be between 55 and 80 years old, postmenopausal, and have a specific level of high blood pressure. They should also be able to walk without help and not be involved in regular vigorous exercise. Participants can expect to engage in an exercise program while being monitored for changes in their blood pressure and overall health. This study aims to provide valuable insights into how exercise timing can be used alongside other treatments for hypertension.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Systolic BP equal to or greater than 130 mmHg without BP medication or greater than 120 mmHg with medication and diastolic blood pressure equal to and greater than 80 mmHg
• • 55-80 years old
• • Post-menopausal female
• • Able to walk without assistance
• Exclusion Criteria:
• • Habitually physically active defined as 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic physical activity per week
• • Overt pulmonary disease/condition as follows: chronic bronchitis, chronic obstructive pulmonary disease, emphysema, or pulmonary hypertension
• • Cardiometabolic disease/condition as follows: diabetes, heart failure, peripheral arterial disease, stroke, coronary artery disease, renal disease, secondary hypertension, chronic venous insufficiency or deep vein thrombosis within last 6 months
• • Cancer within last 5 years
• • Body mass index \>39 kg/m2
• • Current smoking or vape
• • Evening shift work
• • uncontrolled thyroid disorder
• • 2 or more falls in the last year
• • Anemia within 3 months of enrollment
• • Parkinson's disease
• • Dementia
• • Unstable angina
• • Acute pulmonary embolus or infarction
• • Acute myocarditis or pericarditis
• • Acute aortic dissection