Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optical Coherence Tomography Angiography

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Sep 19, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on creating a reference database for a specific eye imaging technology called Optical Coherence Tomography Angiography (OCT-A) using the Spectralis Heidelberg device. This technology helps doctors examine the blood vessels in the retina without needing to inject dye, which makes it safer and easier for patients. The goal is to gather information from healthy volunteers so that doctors can better understand how the blood vessels should look in healthy eyes compared to those with certain eye conditions.

To participate in this trial, you must be an adult (age 18 or older) in good health, with specific eye pressure and vision requirements. Unfortunately, people with certain eye diseases, diabetes, or high blood pressure, among other conditions, cannot join. If you decide to participate, you will undergo a non-invasive eye examination using the OCT-A technology, and your data will contribute to a valuable resource for future eye health studies. This study is currently recruiting participants, and your involvement could help improve eye care for many people.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Voluntary adult subjects or legal representative consenting for minor or subjects under protection
• • Intra ocular pression ≤ 21mmHg
• • Spherical refraction comprised between - 6 D and +6 D and/or axial length between 21 and 26mm
• • Patient affiliated to social security system
• Exclusion Criteria:
• • Ocular diseases: glaucoma, retinal diseases as diabetic retinopathy, age-related macular degeneration, amblyopia, optic neuropathy
• • Diabetes mellitus
• • Uncontrolled hypertension blood pressure (\> 140/90)
• • Recent ocular surgery (\< 6 months)
• • Any ophthalmological conditions interfering with a good ocular examination or OCT quality (cataract, corneal opacity ...)
• • OCT-A sufficient quality ≥ 25 (0 = bad quality /40 = excellent quality
• • Not consenting patient
• • Pathological situation or handicap avoiding good installation