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Search / Trial NCT06048016

Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy Individuals

Launched by CAIRO UNIVERSITY · Sep 19, 2023

Trial Information

Current as of August 19, 2025

Recruiting

Keywords

Alp Scaling Gcf Saliva Periodontitis Health

ClinConnect Summary

This clinical trial is studying how a dental procedure called scaling and root planing affects a specific enzyme called alkaline phosphatase in patients with periodontitis, which is a serious gum disease. The researchers want to compare the alkaline phosphatase levels in the saliva and gum fluid of people who have periodontitis with those who are healthy. By doing this, they hope to understand how effective this treatment is for patients suffering from gum disease.

To participate in this trial, you would need to be diagnosed with periodontitis and have at least 10 teeth remaining. You should also be generally healthy, meaning you shouldn't have certain conditions like diabetes, high blood pressure, or thyroid disease. If you decide to join, you will be asked to follow oral hygiene instructions and will have your saliva and gum fluid tested before and after the treatment. This study is currently looking for participants of all genders, aged between 18 and 65. It’s a great opportunity to contribute to research that may help improve dental treatments for gum disease!

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • periodontitis patients stage I,II,III,IV Having more than 10 remaining teeth. • Systemically free
  • Exclusion Criteria:
  • infectious diseases dependent on antibiotics. .inflammatory diseases depend on analgesics. . Diabetes mellites patients . Hypertensive patients
  • .Thyroid disease
  • Patients who had professional periodontal treatment during the last 6 months.
  • Pregnancy or lactation.
  • Smokers.

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Giza, Haram, Egypt

Patients applied

0 patients applied

Trial Officials

Zahraa Af Nasser

Principal Investigator

Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported