Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects

Launched by CAIRO UNIVERSITY · Sep 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying two different types of grafts used to treat specific dental issues known as intrabony periodontal defects, which are pockets of bone loss in the gums. The goal is to compare the effectiveness of autogenous demineralized dentin—made from the patient's own teeth—against traditional autogenous bone grafts taken from another area of the patient's mouth. Both procedures aim to improve dental health by enhancing bone and tissue attachment. Participants will undergo initial treatments to clean their teeth and prepare for surgery, and then they will receive one of the two grafts using a minimally invasive surgical technique.

To be eligible for this trial, participants need to be at least 18 years old and willing to follow oral hygiene instructions. They should have specific dental conditions, such as a probing depth of 5 mm or more in their gums. Patients with certain health issues or those who smoke cannot participate. Throughout the trial, participants will have follow-up appointments at 1, 3, and 6 months to assess their recovery and the success of the grafting procedure based on various dental health indicators. This study will help determine if the new grafting material is as effective as the standard treatment, which could improve how dental professionals manage these types of gum issues in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patient-related criteria:
• • Motivated patient 18 years of age or order.
• • Patient consulting in the outpatient clinic.
• • Patient ready to perform oral hygiene instructions.
• • Provide informed consent.
• • Accepts the 6 months follow-up period.
• * Teeth related criteria:
• • Tooth with two or three-walled intra-bony defect, probing depth ≥ 5mm with intra osseous defect ≥ 3mm.
• • Mature permanent tooth.
• • Unrestorable tooth or fractured tooth beyond restoration, impacted third molar or supernumerary tooth to be extracted and used as whole tooth graft inside the intrabony defect.
• Exclusion Criteria:
• * Patient-related criteria:
• • Medically compromised patients.
• • Pregnant women.
• • Uncooperative patients.
• • Smokers.
• • Systemic diseases that may compromise healing or bone metabolism (e.g diabetes, hyperthyroidism).
• • Failure to maintain good oral hygiene.
• * Teeth related criteria:
• • Teeth with supra-bony defects.
• • Teeth with grade III mobility.
• • Teeth having interproximal craters, grade III furcation involvement, and grade III mobility.
• • Presence of caries or overhanging restorations.
• • Presence of peri-apical injuries.