Correlation Between Intestinal Blood Flow and Intestinal Dysfunction in Critically Ill Patients

Launched by PEKING UNION MEDICAL COLLEGE HOSPITAL · Sep 16, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how blood flow in the intestines affects the health of critically ill patients. Researchers want to find out if using a special ultrasound technique called color Doppler ultrasonography can help them better understand and monitor blood flow in the intestines. This is important because when patients are very sick, their intestines may not get enough blood, which can lead to complications. By closely monitoring blood flow through the superior mesenteric artery (SMA), the study aims to improve treatment approaches for patients with conditions like sepsis.

To participate in this trial, patients need to be between 18 and 80 years old and have sepsis with an expected stay in the intensive care unit (ICU) of more than three days. However, certain conditions, such as severe heart disease or recent abdominal surgery, may prevent someone from joining. Participants can expect to undergo non-invasive ultrasound tests to evaluate their intestinal blood flow during their ICU stay. This study is still in the early stages, but it could lead to better ways to assess and improve the care of critically ill patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with sepsis with an expected ICU stay of more than 3 days.
• • 2. ≥18 years of age and \<80 years of age.
• Exclusion Criteria:
• • 1. Coronary heart disease, severe mesenteric or abdominal artery stenosis;
• • 2. Fixed body (such as recent spinal surgery or intracranial hypertension);
• • 3. Patients with contraindications for IAP measurement (such as patients who have recently undergone bladder surgery, been injured, or become pregnant;
• • 4. Having undergone abdominal surgery or chest lowering involving the intestines patients undergoing aortic surgery;
• • 5. Poor quality of abdominal ultrasound images;
• • 6. Hydrothorax or ascites.