Faecal Microbiota Transplantation as Means of Preventing Recurrent Urinary Tract Infections

Launched by HELSINKI UNIVERSITY CENTRAL HOSPITAL · Sep 15, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help prevent recurrent urinary tract infections (UTIs) in women by using a treatment called Faecal Microbiota Transplantation (FMT). This method involves transferring healthy bacteria from a donor’s stool into the gut of the participant. The study focuses on women aged 18 and older who have experienced frequent UTIs—specifically, at least two infections in the last six months or three in the past year, with the last one occurring within the last three months.

If you decide to participate in this trial, you will undergo the FMT procedure and then be monitored to see if it helps reduce the number of UTIs you experience. However, there are some important criteria for joining, such as not having any serious gastrointestinal diseases, being free from pregnancy or certain medical conditions that could affect your health. The trial is currently recruiting participants, so this could be an opportunity to help find a new way to manage UTIs while also contributing to medical research.

Gender

FEMALE

Eligibility criteria

• Inclusion criteria:
• • Female subjects aged ≥18
• • History of recurrent UTI: at least two episodes of UTI over the past 6 months or at least three episodes over the past year, most recent episode within the past three months
• • Written informed consent
• Exclusion criteria:
• • Suspected non-compliance
• • Diagnosis of a gastrointestinal disease
• • Pregnancy
• • Immunosuppression
• • Any kind of permanent urinary catheter or intermittent urinary catheterization
• • Any other criteria which, in the investigator's opinion, would compromise the ability of the subject to participate in the study, the subject's well-being, or the outcome of the study