Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis

Launched by UNIVERSITY HOSPITAL OF SPLIT · Sep 20, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating a new way to help diagnose acute appendicitis in children, a condition where the appendix becomes inflamed and can lead to serious complications if not treated quickly. The researchers want to find out if measuring a substance called C-reactive protein (CRP) in saliva is as effective as checking it in the blood. CRP levels often rise when there is inflammation in the body, and being able to use saliva for testing could make the process easier and less invasive for young patients.

To participate in this study, children aged 5 to 17 who are experiencing stomach pain and show signs of appendicitis may be eligible. However, those with a history of chronic or cancer-related illnesses, previous abdominal surgeries, or who are pregnant cannot take part. If selected for the trial, participants will undergo tests that involve collecting samples from both their blood and saliva to see how well these methods work in diagnosing appendicitis. This research aims to ultimately improve diagnosis and treatment for children experiencing this painful condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • children with age from 5 to 17 with acute abdominal pain
• • children with clinical signs of appendicitis
• Exclusion Criteria:
• • previous diagnosis of chronic and/or malignant disease
• • children wich had previous abdominal surgery
• • pregnancy