Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing

Launched by LAWRENCE CHARLES HOOKEY · Sep 18, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how well an Oral Sodium Sulfate Solution (OSS) works for patients who have had trouble with bowel preparation before colonoscopy procedures. Bowel preparation is the process of cleaning out the intestines before the exam, and sometimes it doesn’t go well, which can lead to inadequate results. This study will help determine if OSS can improve the experience and effectiveness for those patients who have previously faced challenges with their bowel prep.

To be eligible for this trial, participants should be between 18 and 80 years old, able to understand English, and have a history of poor bowel preparation as noted by their doctor. However, certain individuals, such as those with certain bowel diseases, recent heart issues, or who are pregnant, cannot participate. If someone joins the study, they will be asked to take the OSS and monitor how well it works for them. This trial is currently recruiting participants, and those who take part will contribute to understanding better ways to prepare for colonoscopies.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients Age 18 to 80 inclusive
• • 2. Able to read and understand the English language
• 3. History of poor bowel prep defined as:
• • Required extensive washing, as noted in the narrative of the endoscopist report.
• • Inadequate preparation
• • Endoscopist recommended shorter interval surveillance due to poor prep
• • adequate for polyps \>5mm but not smaller lesions
• Exclusion Criteria:
• • 1. Patients who have inflammatory bowel disease
• • 2. Patients with ileus or bowel obstruction
• • 3. Patients with history of colorectal resection
• • 4. Patients receiving combined upper and lower endoscopies
• • 5. Patients with ascites
• • 6. Patients with previously documented severe renal impairment
• • 7. Unable to provide consent
• • 8. Pregnant or lactating female (females of child-bearing potential will undergo urine pregnancy testing)
• • 9. Patients who have had a recent myocardial infarction(\<6months)