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Search / Trial NCT06051981

White Spot Lesions Treatment in Orthodontic

Launched by RIYADH ELM UNIVERSITY · Sep 18, 2023

Trial Information

Current as of July 25, 2025

Not yet recruiting

Keywords

Fixed Orthodontic Appliances White Spot Lesion Fluoride Varnish Casein Phosphopeptide Amorphous Calcium Phosphate Resin Infiltration Laser Fluorescence

ClinConnect Summary

This clinical trial is looking at a new way to treat white spot lesions (WSLs), which are small, white marks on teeth that can appear after wearing braces. These spots can happen when the enamel, or outer layer of the tooth, loses minerals. The study will compare four different treatments: a control group with no treatment, fluoride varnish, a special milk-based product, and a method called resin infiltration, which helps seal the teeth. Researchers will recruit 22 patients from Riyadh Elm University who have these white spots and will examine their teeth to see how effective each treatment is.

To qualify for the study, participants must be post-orthodontic patients with one white spot on the surface of their tooth that is not too severe (ICDAS Code 1 or 2). They need to agree to participate and, if they are younger, their parents must give consent. Unfortunately, those with certain dental defects, specific health conditions, or allergies to the study treatments cannot take part. If you join the study, you can expect to visit the dental clinic for examinations and to receive one of the treatments being tested. This trial aims to find the best way to help improve the appearance of these white spots and keep your teeth healthy after orthodontic treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Post orthodontic patients with one WSLs on buccal surface of tooth with ICDAS Code 1 or 2.
  • 2. Agreeing to participate in the study by singing the study informed consent.
  • 3. For younger patients parents agree to provide consent for child participation in the study.
  • Exclusion Criteria:
  • 1. Developmental defects of dental hard tissue
  • 2. Patients who have systemic disease or under medications that usually cause an increased risk of oral caries.
  • 3. Patients who are allergic to Fluoride varnish, CPP-ACP and resin infiltration.

About Riyadh Elm University

Riyadh Elm University is a leading educational and research institution in Saudi Arabia, dedicated to advancing healthcare through innovative clinical research and evidence-based practice. Committed to fostering academic excellence and community health, the university collaborates with local and international partners to conduct clinical trials that aim to improve patient outcomes and contribute to the global body of medical knowledge. With a focus on ethical standards and regulatory compliance, Riyadh Elm University seeks to drive advancements in medical science while prioritizing the safety and well-being of participants involved in its research initiatives.

Locations

Patients applied

0 patients applied

Trial Officials

Samira Algasn, BDS

Principal Investigator

Riyadh Elm University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported