A Study of Adipose Tissue in Adaptive Responses to Exercise

Launched by MAYO CLINIC · Sep 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how exercise affects fat tissue in the body and how these changes might help improve health, especially as we age or for those who are obese. Researchers want to understand how our fat tissue responds to exercise and if these responses can lead to better overall health. They are currently looking for participants who are healthy adults aged 18-35 or 65-85, with a body mass index (BMI) that is either under 28 or between 30 and 40. Participants should have been at a stable weight for at least three months.

If you join this study, you will be part of research that could help us learn more about the benefits of exercise on fat tissue. However, certain conditions might prevent you from participating, such as regularly exercising, smoking, or having specific health issues like heart disease or liver problems. This trial is a great opportunity to contribute to important health research while also potentially gaining insights into how your body responds to exercise.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults between the ages of 18-35 OR 65-85.
• • BMI 18.5 kg/m2 - 40 kg/m2
• • Weight stable (≥ 3 months)
• • Generally healthy
• Exclusion Criteria:
• • Participation in ≥ 30 minutes of structured physical activity ≥ 2 days per week.
• • Smoking/tobacco use.
• • Alcohol/substance abuse.
• • Pregnancy and breastfeeding.
• • Anemia.
• • Abnormal renal function.
• • Blood clotting disorders.
• • Coronary artery disease.
• • Uncontrolled thyroid disease.
• • Liver disease.
• • Use of medications known to influence the main outcomes of the study.
• • Orthopedic problems that may be aggravated by exercise.
• • Chronic disease at the discretion of the investigators.