Perioperative Adiponectin and Postoperative Inflammatory Response After Major Abdominal Surgery

Launched by OSIJEK UNIVERSITY HOSPITAL · Sep 25, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how certain levels of a protein called adiponectin in the blood may affect the body's response to inflammation after major abdominal surgery. The researchers believe that lower levels of adiponectin could lead to a stronger inflammatory response, which might cause complications in patients who are overweight or obese. By studying this relationship, the trial aims to help improve patient outcomes and reduce the risk of severe complications after surgery.

To participate in this trial, you need to be at least 18 years old and scheduled for major elective abdominal surgery related to a gastrointestinal condition, such as a tumor. The study is open to all genders, but patients with certain conditions, like acute infections or those on specific medications, cannot participate. If you join the trial, you can expect to have your blood levels of adiponectin measured before and after surgery, and your health will be monitored to see how your body reacts. This study could provide valuable insights into how to better manage postoperative care for patients, especially those who are obese.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \>18 years Patient presenting for major elective abdominal surgery of gastrointestinal system according to tumor.
• Exclusion Criteria:
• • Age\<18 years BMI\<18.5kg/m2 Acute surgical conditions Established acute systemic/local infection Chronic/actual corticosteroid therapy Active immunomodulation therapy Allergie to used anestehetics/analgetics in study.