Magnetic Resonance Imaging (MRI) and Eye-tracking Predictive Markers of Cognitive Ageing.
Launched by UNIVERSITY HOSPITAL, TOULOUSE · Sep 21, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "MRI and Eye-tracking Predictive Markers of Cognitive Ageing," is studying how certain brain markers might help us understand cognitive changes in healthy older adults, specifically those over 60 years old. The focus is on a part of the brain called the locus coeruleus, which produces a chemical important for brain function. Researchers will use MRI (a type of brain scan) and eye-tracking technology to see how these markers relate to thinking and memory abilities.
To participate, individuals must be part of the INSPIRE cohort, score at least 27 out of 30 on a mental health test, and have regular internet access. Participants cannot have any conditions that would prevent them from having an MRI or affect eye tracking, such as certain eye diseases or neurological disorders. Those who join can expect to undergo some tests and provide valuable information that could help in understanding how aging affects the brain.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • INSPIRE cohort participant
- • Mini-Mental State Examination score ≥ 27 on 30
- • Access to a web connection from participant's or relative's home and regular use of web surfing
- • Signature of the informed consent
- • Affiliated to a social security scheme
- Exclusion Criteria:
- • Any contra-indications to MRI exam
- • Ophthalmic pathology impacting eye-tracking measures
- • Neurological or psychiatric pathology
- • Person under guardianship or curatorship
- Contraindications to MRI examination:
- • Pacemaker or cardiac defibrillator
- • Implanted material activated by an electrical, magnetic or mechanical system
- • Haemostatic clips for intracerebral aneurysms or carotid arteries
- • Orthopedic implants
- • Claustrophobia
- Ophthalmological pathologies impacting eye tracking measurements:
- • Glaucoma
- • Age-related macular degeneration
- • Unoperated cataract
About University Hospital, Toulouse
The University Hospital of Toulouse is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on patient-centered care, the hospital integrates cutting-edge scientific inquiry with comprehensive clinical services. Its multidisciplinary team of healthcare professionals collaborates with renowned researchers to facilitate pioneering studies across various medical fields, aiming to enhance treatment options and improve patient outcomes. As a prominent institution in the region, the University Hospital of Toulouse is committed to fostering an environment of excellence in both education and research within the healthcare community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Toulouse, , France
Toulouse, , France
Patients applied
Trial Officials
Pierre PAYOUX, MD
Principal Investigator
University Hospital, Toulouse
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported