Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Sep 25, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a traditional medicine called Yunnan Baiyao, which has been used for over 120 years to treat various wounds. The focus of this study is to understand how effective Yunnan Baiyao is in treating diabetic foot, a serious complication that can occur in people with diabetes. Researchers want to gather more evidence on how to best use this treatment at different stages of diabetic foot. They will also analyze tissue samples from patients to identify the specific ways Yunnan Baiyao may help with healing.

To participate in the trial, you must be between 18 and 80 years old, diagnosed with diabetes and diabetic foot, and willing to sign an informed consent form. However, there are some health conditions that might prevent you from joining, such as severe heart issues or uncontrolled blood sugar levels. If you do participate, you can expect to receive treatment with Yunnan Baiyao and be part of an important study that aims to improve healing for diabetic foot patients. Your involvement could help clarify how this traditional medicine works and lead to better treatment options in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. The age of the subjects is 18-80 years old;
• • 2. Diagnose diabetes according to WHO standards;
• • 3. Diagnosis of Diabetic foot;
• • 4. Confirmed as one of the stages of infection progression and granulation growth;
• • 5. Voluntarily participate in this study and sign an informed consent form.
• Exclusion Criteria:
• • 1. Severe diseases such as acute myocardial infarction, heart failure, hepatitis, shock, and respiratory failure have not been corrected yet;
• • 2. Blood glucose is out of control, Glucose test#Fasting blood sugar\>15mmol /L, Glycated hemoglobin\>12%;
• • 3. There is active bleeding inside the wound, and routine basic treatment plans cannot be implemented;
• • 4. Serum albumin\<20g/L; Hemoglobin\<60g/L; Platelets\<50 × 109/L;
• • 5. Late stage subjects with malignant tumors;
• • 6. Active period of autoimmune diseases;
• • 7. Have a history of allergy to Yunnan Baiyao;
• • 8. The subject is unable to cooperate or has mental disorders;
• • 9. According to the judgment of the researcher, the subject has a clear reason that cannot be removed and affects wound healing, which is not suitable for this study or cannot comply with the requirements of this study.