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Search / Trial NCT06064682

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

Launched by JONSSON COMPREHENSIVE CANCER CENTER · Sep 26, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Osteosarcoma

ClinConnect Summary

This clinical trial, called "An Organoid-based Functional Precision Medicine Trial in Osteosarcoma," is focused on understanding how patients with osteosarcoma, a type of bone cancer, might respond to different chemotherapy treatments. The researchers aim to use small samples of the tumor, obtained during routine biopsies or surgeries, to see how these cancer cells behave in the lab. By doing this, they hope to identify which chemotherapy drugs are most likely to work for each patient, based on how their specific cancer cells react. Additionally, the study will look at the genetic makeup of the tumors to gain more insights into osteosarcoma.

If you are considering participating in this trial, you may be eligible if you have imaging results that suggest osteosarcoma and are scheduled for a biopsy or surgery to confirm the diagnosis. This trial is open to all genders and is currently recruiting participants. Those involved can expect to contribute to important research that may help improve treatment options for future patients with osteosarcoma, while also receiving additional information about their own tumor's characteristics.

Gender

ALL

Eligibility criteria

  • Inclusion / exclusion criteria - Group1:
  • - Patients without diagnosis of osteosarcoma and whose imaging studies are suggestive of osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes
  • Inclusion / exclusion criteria - Group 2:
  • - Patients whose imaging studies are suggestive of metastatic osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

About Jonsson Comprehensive Cancer Center

The Jonsson Comprehensive Cancer Center (JCCC) is a leading research and treatment institution dedicated to advancing cancer prevention, diagnosis, and treatment through innovative clinical trials and cutting-edge research. Affiliated with the University of California, Los Angeles (UCLA), the JCCC integrates a multidisciplinary approach, bringing together experts in oncology, genetics, and public health to foster collaboration and translate scientific discoveries into effective therapies. With a commitment to improving patient outcomes and quality of life, the JCCC conducts a wide range of clinical trials aimed at addressing various cancer types, ensuring that patients have access to the most advanced therapeutic options available.

Locations

Los Angeles, California, United States

Patients applied

0 patients applied

Trial Officials

Alice Soragni, PhD

Principal Investigator

University of California at Los Angeles

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported