Standardised Drug Provocation Testing in Perioperative Hypersensitivity

Launched by UNIVERSITY HOSPITAL, ANTWERP · Sep 26, 2023

Keywords

ClinConnect Summary

This clinical trial is designed to study the safety and effectiveness of a specific testing method called drug provocation testing in patients who may have had allergic reactions during surgery. The researchers want to find out how well this testing works when patients receive anesthetic medications at normal doses. This is particularly important for adults who are being evaluated for possible drug allergies related to anesthesia.

To participate in the trial, you need to be an adult who has experienced symptoms of an allergic reaction during surgery, and you should be visiting the allergology department at the Antwerp University Hospital. You will also need to agree to undergo thorough testing and sign consent forms. If you join the study, you can expect to receive careful monitoring and support throughout the testing process. It’s crucial to note that anyone who doesn't want to participate or does not meet the specific criteria won't be included in the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients consulting the allergology department of the Antwerp University hospital medical with a history consistent with perioperative hypersensitivity
• • Indication for diagnostic work-up as determined at an interdisciplinary meeting between allergologists and anaesthetists
• • willing to sign separate informed consent forms for both general anaesthesia and the Drug Provocation Test.
• Exclusion Criteria:
• • patient refusal
• • incomplete diagnostic work-up
• • history inconsistent with perioperative hypersensitivity