Gastric Residual Volumes in Infants Fed at 4 and 6 Hours Prior to General Anaesthesia

Launched by KING'S COLLEGE HOSPITAL NHS TRUST · Sep 28, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at the safety of how long infants should fast before undergoing general anesthesia. Current guidelines in the UK recommend that babies who are fed formula should not eat for 6 hours before anesthesia, while some European guidelines suggest a shorter fasting time of 4 hours. This study aims to understand how much formula is left in the stomach at these different fasting times and how it might affect safety during anesthesia.

Eligible participants for this trial include healthy infants who are at least 37 weeks old (either born at that time or corrected for prematurity) and up to 12 months old, who are fed formula. However, babies with certain health conditions, such as significant reflux or serious breathing or heart problems, cannot take part. If your child is eligible and decides to participate, they will be involved in a study that aims to improve safety during anesthesia by learning more about how long they should fast before the procedure. The trial is not yet recruiting participants, so there will be more information available later.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Term or term corrected (\> 37 weeks) upto 12 months Formula fed ASA 1-3
• Exclusion Criteria:
• • Significant reflux Co-administration of drugs known to impact gastric motility or PH of gastric contents Significant respiratory comorbidity including chronic lung disease on home oxygen Significant cardiac comorbidity