Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
Launched by CHILDREN'S MERCY HOSPITAL KANSAS CITY · Sep 28, 2023
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Patients will assigned to one of two groups. Either the intervention group where they will receive a dexmedetomidine infusion at 0.2mcg/kg/hr for 48 hours post-operatively or the control group where they will receive a normal saline infusion for 48 hours post-operatively in addition to our hospitals standard pain management protocol. Pain scores will be recorded and patients will fill out a brief questionnaire every 48hours about their pain control and side effects (pruritus, nausea, vomiting, drowsiness).
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosis of idiopathic scoliosis
- • Undergoing a posterior spinal fusion of at least 5 levels with both thoracic and lumbar involvement
- Exclusion Criteria:
- • Known allergy to dexmedetomidine or any of the standard medications used intra or post operatively
- • Patients with a history of chronic pain currently taking opioids, TCA's, Gabapentinoids
- • Medical contraindications to administration of dexmedetomidine, unstable cardiac status, (prolonged Qtc, life threatening arrhythmias, use of digoxin)
- • Moya Moya disease
About Children's Mercy Hospital Kansas City
Children's Mercy Hospital Kansas City is a renowned pediatric healthcare institution dedicated to advancing the health and well-being of children through innovative research and clinical trials. As a leading sponsor of clinical trials, the hospital focuses on developing and testing new treatments and therapies that address a wide range of pediatric conditions. With a commitment to excellence in patient care and a collaborative approach to research, Children's Mercy is at the forefront of pediatric medicine, striving to improve outcomes and enhance the quality of life for children and their families.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kansas City, Missouri, United States
Patients applied
Trial Officials
Nichole M Doyle, MD
Principal Investigator
Children's Mercy Hospital Kansas City
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported