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Search / Trial NCT06067893

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

Launched by CHILDREN'S MERCY HOSPITAL KANSAS CITY · Sep 28, 2023

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Pain Management Narcotic Sparing Pediatric Dexmedetomidine

ClinConnect Summary

Patients will assigned to one of two groups. Either the intervention group where they will receive a dexmedetomidine infusion at 0.2mcg/kg/hr for 48 hours post-operatively or the control group where they will receive a normal saline infusion for 48 hours post-operatively in addition to our hospitals standard pain management protocol. Pain scores will be recorded and patients will fill out a brief questionnaire every 48hours about their pain control and side effects (pruritus, nausea, vomiting, drowsiness).

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of idiopathic scoliosis
  • Undergoing a posterior spinal fusion of at least 5 levels with both thoracic and lumbar involvement
  • Exclusion Criteria:
  • Known allergy to dexmedetomidine or any of the standard medications used intra or post operatively
  • Patients with a history of chronic pain currently taking opioids, TCA's, Gabapentinoids
  • Medical contraindications to administration of dexmedetomidine, unstable cardiac status, (prolonged Qtc, life threatening arrhythmias, use of digoxin)
  • Moya Moya disease

About Children's Mercy Hospital Kansas City

Children's Mercy Hospital Kansas City is a renowned pediatric healthcare institution dedicated to advancing the health and well-being of children through innovative research and clinical trials. As a leading sponsor of clinical trials, the hospital focuses on developing and testing new treatments and therapies that address a wide range of pediatric conditions. With a commitment to excellence in patient care and a collaborative approach to research, Children's Mercy is at the forefront of pediatric medicine, striving to improve outcomes and enhance the quality of life for children and their families.

Locations

Kansas City, Missouri, United States

Patients applied

0 patients applied

Trial Officials

Nichole M Doyle, MD

Principal Investigator

Children's Mercy Hospital Kansas City

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported