Prehabilitation in Pancreatic Surgery

Launched by IRCCS SAN RAFFAELE · Sep 29, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how a special four-week program, called prehabilitation, can help patients with localized pancreatic or periampullary cancer before they have surgery. The program includes exercises and nutritional support aimed at improving patients' health and well-being. Researchers want to see if this prehabilitation can reduce complications after surgery, improve patients' physical and nutritional status, and enhance their overall quality of life. They will also look at specific markers in the blood related to muscle loss and weight loss associated with cancer.

To be eligible for this trial, participants must be at least 18 years old and scheduled for surgery to remove their pancreatic or periampullary cancer. They should be able to give informed consent and not have any conditions that would prevent them from participating in the prehabilitation program, such as severe health issues or being pregnant. Participants will be randomly assigned to either the group that receives the prehabilitation program or a control group that does not. This study is currently recruiting participants, and it welcomes individuals of all genders within the age range of 65 to 74.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years
• • Indication for curative resection for pancreatic or periampullary cancer
• • Signed Informed consent
• Exclusion Criteria:
• • Metastatic or unresectable disease found preoperatively
• • Comorbidities contraindicating prehabilitation regimen (exercise and nutritional intervention) such as orthopedic, cognitive disabilities, chronic renal failure (dialysis or creatinine \>250 mmol)
• • ASA score 4-5
• • Pregnancy
• • Illiteracy (inability to read and understand Italian language)