Multiple Micronutrient Supplementation (MMS) Iron Dose Acceptability Crossover Trial

Launched by GEORGE WASHINGTON UNIVERSITY · Sep 29, 2023

Keywords

ClinConnect Summary

This clinical trial, called the Multiple Micronutrient Supplementation (MMS) Iron Dose Acceptability Crossover Trial, is looking at how well different amounts of iron in vitamin supplements are accepted by pregnant women. Specifically, the study will compare supplements that contain 30 mg, 45 mg, and 60 mg of iron to see which one women prefer and how they feel about any possible side effects.

To participate in this trial, women need to be pregnant and less than 15 weeks along, at least 18 years old, and planning to stay in Dar es Salaam during the study. They should also be attending their first prenatal care visit at the clinic. However, women with severe anemia or certain blood disorders, like sickle cell disease, cannot join. If you take part, you can expect to try different iron supplements and share your experiences regarding their taste, how easy they are to take, and any side effects you might notice. This study aims to help improve nutritional support for pregnant women in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Attending first ANC visit at the study clinic
• • Pregnant women ≤ 15 weeks of gestation
• • Aged ≥ 18 years
• • Intending to stay in Dar es Salaam for the duration of study
• • Provides informed consent
• Exclusion Criteria:
• • Severe anemia (defined as Hb \<8.5 g/dL per Tanzania standard of care)
• • Sickle cell disease (SS,SC, CC genotype) as tested by HemoTypeSC
• • Concurrent participation in other nutritional supplementation trial
• • Pregnant women with disability or condition which would impair their ability to provide informed consent and complete study procedures.