Wound Healing After Endoscopic Sinus Surgery

Launched by ASSIUT UNIVERSITY · Oct 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how a special ointment made with Thymoquinone and olive oil may help wounds heal after endoscopic sinus surgery, which is often needed for people with nasal polyps or chronic sinusitis. The trial is not yet recruiting participants, but it will involve patients aged 6 to 74 who have both clinically diagnosed and confirmed cases of nasal polyps that require surgery.

To participate, patients must not have certain medical conditions, such as asthma or a history of allergic reactions to the ingredients being tested, and they should not be pregnant or breastfeeding. Those who are interested in joining the study can expect to receive the ointment after their surgery and will be monitored to see how well it helps their healing process. Overall, this trial aims to find better ways to support recovery for patients undergoing this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - All patients who will be clinically diagnosed and radiologically confirmed cases with bilateral nasal polyposis indicated for Endoscopic sinus surgery.
• Exclusion Criteria:
• • 1. Unfit patient for surgery
• • 2. Pregnant and lactating women.
• • 3. Patients unwilling to participate.
• • 4. Patients who have unilateral disease.
• 5. Patients with a history of the following underlying medical conditions, which are associated with an increased rate of revision surgery, will be excluded from the study:
• • 1. Aspirin intolerance
• • 2. Asthma
• • 3. Mucociliary disorder
• • 4. Immunocompromised status.
• • 6. Patients with known allergic reactions to Thymoquinone or olive oil.
• • 7. Injury of the orbit with any tear in the periorbital area.