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Search / Trial NCT06070649

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Launched by YALE UNIVERSITY · Oct 1, 2023

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is exploring the potential benefits of a substance called DMT, along with therapy, for people struggling with Alcohol Use Disorder (AUD). AUD is a medical condition where individuals have difficulty controlling their drinking, which can lead to serious health problems. The study will be conducted in a controlled setting where some participants will receive DMT combined with therapy, while others will receive a placebo, which is a treatment that looks like the real medication but has no active ingredients. This is done to see if DMT really helps improve the condition.

To be eligible for this trial, participants must be between the ages of 18 and 65 and have a diagnosis of Alcohol Use Disorder. They should be in good health and able to give their consent to participate. However, individuals with unstable medical conditions will not be able to join the study. While the trial is not yet recruiting, those who participate can expect to receive careful support and monitoring throughout the study to ensure their safety and well-being. This is an important step in understanding new ways to help people with alcohol-related issues.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) diagnosis of Alcohol Use Disorder
  • Medically healthy
  • Ability to provide consent
  • Exclusion Criteria:
  • Unstable medical conditions

About Yale University

Yale University, a prestigious Ivy League institution located in New Haven, Connecticut, is renowned for its commitment to advancing medical research and clinical innovation. With a rich history of academic excellence and a robust infrastructure for scientific inquiry, Yale serves as a leading sponsor for clinical trials aimed at improving patient care and developing new therapeutic approaches. The university's multidisciplinary teams of researchers and clinicians collaborate to conduct rigorous and ethical studies, leveraging cutting-edge technologies and methodologies to address critical health challenges. Through its dedication to fostering an environment of inquiry and discovery, Yale University plays a pivotal role in translating research findings into clinical practice, ultimately enhancing health outcomes for diverse populations.

Locations

New Haven, Connecticut, United States

Patients applied

0 patients applied

Trial Officials

Anahita Bassir Nia, MD

Principal Investigator

Yale University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported