The Effect of Platelet-rich Fibrin and Vitamin Dꝫ Injections on Canine Retraction
Launched by BENI-SUEF UNIVERSITY · Oct 1, 2023
Trial Information
Current as of July 12, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how two different treatments—Platelet-rich Fibrin (PRF) injections and Vitamin D injections—can help speed up the movement of canine teeth in patients who need orthodontic treatment. Specifically, the researchers want to see if these treatments affect the rate at which the teeth move and if they have any impact on the thickness of the surrounding bone.
To be eligible for this study, participants should be between 18 and 40 years old and have a specific type of dental misalignment that requires the removal of certain teeth and movement of the canine teeth. They should also have good to fair oral hygiene and no active gum disease. If you join this study, you can expect to receive one of the two treatments and have regular check-ups to monitor how well the treatments are working. The trial is currently recruiting participants, and it’s important to note that those with certain health conditions or poor oral hygiene may not qualify.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age: 18- 40 years old.
- • 2. Angle Class I or Class II dental malocclusion that required bilateral maxillary first premolar extraction and upper canine retraction as a part of the treatment plan.
- • 3. Good to fair oral hygiene.
- • 4. Normal probing depth.
- Exclusion Criteria:
- • 1. Active periodontal disease.
- • 2. Poor oral hygiene.
- • 3. Systemic diseases or medications that alter bone metabolism or tooth movement.
- • 4. Craniofacial anomalies.
About Beni Suef University
Beni-Suef University is a prominent academic institution in Egypt dedicated to advancing medical research and clinical trials aimed at improving healthcare outcomes. With a strong emphasis on innovation and collaboration, the university fosters a multidisciplinary approach to research, engaging faculty, students, and healthcare professionals in the pursuit of scientific knowledge. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring that all clinical trials conducted under its auspices are designed to enhance patient care and contribute to the global body of medical research. Through its initiatives, Beni-Suef University aims to translate research findings into practical applications that benefit communities locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Banī Suwayf, Beni Suef Governorate, Egypt
Patients applied
Trial Officials
Rehab Khalil
Principal Investigator
Faculty of Dentistry, Beni Suef University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported