The Effects of Almond on Facial Skin Collagen and Wrinkles

Launched by INTEGRATIVE SKIN SCIENCE AND RESEARCH · Oct 6, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how eating almonds might affect the health of facial skin, specifically looking at collagen production, wrinkles, and skin elasticity in women. Collagen is a protein that helps keep skin firm and smooth, while wrinkles and pigmentation changes can make skin look older. The trial will include both premenopausal and postmenopausal women aged 35 to 70, with participants being split evenly between these two groups. To be eligible, participants should have a stable diet and skincare routine they've been following for at least six months and should not have any nut allergies.

Women who join the study can expect to maintain their usual diet and skincare products while consuming a specific amount of almonds over a set period. It's important to note that certain individuals, such as those with a nut allergy, recent cosmetic procedures, or specific medical conditions, will not be able to participate. By joining this trial, participants will help researchers understand if almonds can play a role in improving skin health, which could be beneficial for many women looking to maintain a youthful appearance.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Subjects 35 to 70 years of age of all skin types
• • 50% of the subjects will be postmenopausal women determined as \>1-year loss of menstrual period
• • 50% of the subjects will be premenopausal women
• • BMI 18.5 - 35 kg/m2
• • Individuals with a habitual diet that has been maintained for at least 6 months and to be maintained for the duration of the study
• • Individuals must maintain their usual skincare products, defined as products that has been used for at least 1 month, for the duration of the study
• Exclusion Criteria:
• • Those with a nut allergy
• • Those who are unwilling to discontinue oral collagen supplementation 1 month prior to the start of the study
• • Individuals who are unwilling to discontinue vitamin E or nut containing supplements 2 weeks prior to and during the intervention.
• • Individuals who are pregnant or breastfeeding
• • Change in skincare products during the study
• • Had a medical or cosmetic procedure such as laser resurfacing or plastic surgery to the face within the last 6 months (include botulinum toxin, dermal fillers, collagen, or other similar cosmetic procedure)
• • Has an autoimmune photosensitive condition or known genetic condition with a deficiency in collagen production (such as Ehler-Danlos)
• • Those with a skin disease on their face that would affect the assessment of their skin based on the assessment of the investigator.
• • Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years