Protein Digestion After Bariatric Surgery in Older Adults

Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Oct 6, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how well older adults digest dietary protein, particularly looking at differences between those who have had weight loss surgery (bariatric surgery) and those who have not. The researchers want to find out how common a condition called sarcopenia, which is the loss of muscle mass and strength, is among these groups. They are particularly focused on older adults, aged 65 and above, to understand the factors that may influence their muscle health.

To participate in this trial, you need to be at least 65 years old and fall into one of three groups: you have had bariatric surgery within the last 1 to 10 years, or you have not had any weight loss surgery. Unfortunately, if you have serious health issues like advanced organ failure, certain cancers, or specific gastrointestinal conditions, you would not be eligible to join. If you take part, you can expect to share your health history and possibly undergo some tests to help researchers gather important information about muscle health in relation to protein digestion.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent
• • Group 1,2,3: Age 65 years or older
• • Group 4,5,6: Age 18 to 65 years
• • Group 1,2,4,5: Previous bariatric surgery for obesity 1 - 10 years ago
• • Group 3,6: No previous weight loss surgery
• Exclusion Criteria:
• • Current diagnosis of cancer
• • Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage 4.
• • Immobility
• • Neuromuscular degenerative conditions
• • Gastrointestinal conditions including coeliac disease, Crohn's disease, previous resection of the small intestine, gastroparesis
• • Unable to follow the procedures of the studies due to cognitive impairment such as diagnosed dementia.
• • Allergy/intolerance to milk, or soy or spirulina